Hampshire helped invent the notion of interdisciplinary education, based on the idea that questions and issues are best examined from multiple perspectives.

Instead of traditional, single-discipline departments, Hampshire's curriculum is organized into five interdisciplinary schools:

	Transcending Boundaries
	Students may want to combine talents within the arts, such as writing and photography, with a particular cultural interest. Or they may want to address problems of war and peace, of environmental policy, or of the uses of new information technology, which demand scientific as well as political, economic, and ethical understanding.

School of Cognitive Science
The School of Cognitive Science (CS) engages students with interests ranging from psychology, philosophy, and neuroscience to animal behavior, child development, computer science, digital multimedia, and linguistics.

School of Critical Social Inquiry
The School of Critical Social Inquiry (CSI) includes faculty trained in history, psychology, psychoanalysis, anthropology, economics, sociology, politics, law, philosophy, cultural studies, and education. What unites CSI is a common commitment to understanding the processes of social and cultural formations and their implications.

School of Humanities, Arts, and Cultural Studies
School of Humanities, Arts, and Cultural Studies (HACU) students' interests range from philosophy, literature, film, video, photography, history, dance, painting, art history, cultural theory and history, critical theory, religious studies, studio arts, ancient studies, music, American studies,  media studies, environmental design, and architecture. 

School for Interdisciplinary Arts
In the School for Interdisciplinary Arts (IA), students and professors work across boundaries of art forms such as theatre, sculpture, writing, literature, children's theatre, creative drama, and arts and social action.

School of Natural Science
School of Natural Science (NS) students involve themselves in original scientific research. Areas of interest include environmental sciences, agricultural studies, health sciences, and more.